About Tamara Wexler, MD, PhD

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Dr. Wexler is an internationally recognized endocrinologist specializing in neuroendocrinology and reproductive endocrinology. She has served as an Attending Physician in Internal Medicine at the Massachusetts General Hospital and as the founding Director of the NYU Langone Medical Center Pituitary Center. Her research efforts focus on pituitary dysfunction after brain injury.

Dr. Wexler received her MD and her PhD in Neuroscience from the University of Pennsylvania. She completed her Internal Medicine residency and Endocrinology fellowship at the Massachusetts General Hospital, where she was part of the Neuroendocrine Unit, designed and ran national clinical trials on the effects of growth hormone, and served for 12 years on the Optimum Care Committee.

While on staff at the MGH, Dr. Wexler spent four years at McKinsey & Company, where she served as the Global Endocrinology Lead. She is an elected member of the Endocrine Society Clinical Guidelines Committee and of the University of Pennsylvania Institute for Diabetes, Obesity, and Metabolism Leadership Council, reviewed grants for the Bill and Melinda Gates Foundation in the area of reproductive health, and serves on the editorial board of Endocrine Today. She is a speaker and moderator at academic medical centers and national conferences on the topic of pituitary function, reproductive endocrinology, and post-TBI endocrine disorders.  Her publications appear in the Journal of Clinical Endocrinology & Metabolism and Clinical Endocrinology, among other journals.

Neuroendocrine Associates

Dr. Wexler started Neuroendocrine Associates in order to offer reproductive endocrine and neuroendocrine care to patients across the United States, with a focus on patient education and direct time with patients. She offers telemedicine in many states, and has a clinic in Virginia.  

She continues to direct research efforts at the Rusk Rehab Center of NYU as a Clinical Professor, and holds an adjunct professorship at the University of Pennsylvania.

Education

Clinical and Research Fellowship in Endocrinology, Diabetes and Metabolism at the Massachusetts General Hospital

Program in Clinical Effectiveness, Harvard School of Public Health  

Residency in Internal Medicine at the Massachusetts General Hospital

Medical degree from the University of Pennsylvania (AOA)

PhD in Neuroscience from the University of Pennsylvania

BA from Princeton University

Affiliations and Certifications

Clinical Professor, NYU Langone

Adjunct Associate Professor of Medicine, University of Pennsylvania School of Medicine

Board-certified in Endocrinology, Diabetes and Metabolism

Board-certified in Internal Medicine

Select Publications

Wexler TL, Gunnell L, Omer Z, Kuhlthau K et al. Growth Hormone Deficiency is Associated with Decreased Quality of Life in Patients with Prior Acromegaly.  J Clin Endocrinol Metab. 2009 July; 94(7): 2471-77

Lawson EA, Donoho D, Miller KK, Misra M, Meenaghan E, Lydecker J, Wexler TL, Herzog D, Klibanski A.  Hypercortisolemia is associated with severity of bone loss and depression in hypothalamic amenorrhea and anorexia nervosa.  J Clin Endocrinol Metab, 2009 Dec; 94(12): 4710-4716.

Miller, KK, Wexler, TL, Fazeli P, Gunnell L et al. Growth Hormone Deficiency Following Treatment of Acromegaly: A Randomized, Placebo-Controlled Study of Growth Hormone Replacement.  J Clin Endocrinol Metab, 2010 Feb;95(2):567-77. [Presented in The Year in Pituitary review, 2010 Endocrine Society annual meeting]

Wexler TL, Durst R, McCarty D, Omer Z, Gunnell L, Miller KK, Picard M, Klibanski A.  GH Status Predicts Left Ventricular Mass in Patients after Cure of Acromegaly.  Growth Hormone & IGF Research, 2010 Oct; 20(5): 33-37. [Presented in oral symposium, 2010 Endocrine Society annual meeting]

Wexler TL. Pituitary Dysfunction. In JM Silver, TW McAllister, DB Arciniegas (Eds) Textbook of Traumatic Brain Injury, 3rd edition (chapter 30). 2019. Washington, DC: American Psychiatric Association Publishing

Wexler TL Neuroendocrine dysfunction. In N Zasler, D Katz, R Zafonte (Eds), Brain Injury Medicine. 2021. New York, NY: Springer Publishing Company

Yuen KCJ, Masel B, Jaffee MS, O’Shanick G, Wexler TL et al., A Consensus on Optimization of Care in Patients with Growth Hormone Deficiency and Mild Traumatic Brain Injury, Growth Hormone & IGF Research, 2022

Wexler TL, Page-Wilson G, Dopamine Agonists for the Treatment of Pituitary Tumors: From Ergot Extracts to Next Generation Therapies, Brit J Clin Pharmacol, 2023

Wexler TL, Reifschneider K, Backeljauw P, et al. Growth Hormone Deficiency Following Traumatic Brain Injury in Pediatric and Adolescent Patients: Presentation, Treatment, and Challenges of Transitioning From Pediatric to Adult Services. J Neurotrauma, 2023

Wexler TL. Neuroendocrine Disruptions Following Head Injury, Curr Neurol Neurosci Rep, 2023

Reviews, Video, and Podcast links

Wexler TL, Weight and Fertility, Endoscan, 2014 May; 5(2)

Wexler TL, Male Weight and Fertility, Endoscan, 2014 Aug; 5(3)

Wexler TL, Growth Hormone: The Goldilocks Principle. An overview of GH, and the impact of GH replacement, Endoscan, 2015 Apr; 6(2).

Wexler TL, Testosterone Use in Men: 2016 Update, Endoscan, 2016 Apr; vol 7(2) 

Pituitary Dysfunction after TBI (March 2018)

New Testosterone Replacement Guidelines (March 2018)

Neuroendocrine Dysfunction after TBI: What Patients and Families Should Know (July 2020 presentation)

Podcast on Pituitary Issues after Brain Injury, part 1 and part 2

Hormonal Havoc: Imbalance after Injury (Podcast, with Making Headway)

Live talk on Pituitary World News with Dr. Lewis Blevins: Pituitary dysfunction after TBI

In June (2023), Dr. Wexler discussed the impact of hormone deficiencies after TBI, and the role of endocrinologists: Effects of hormone changes after concussions